The clinical activity is performed by a multidisciplinary team working with physicians specialized in different areas of transplantation medicine and surgery, and vital organ failure (liver, kidney, heart, lung and pancreas). The team establishes custom therapeutic programs for each patient.

All transplant techniques, involving both cadaveric and living donors, are performed at ISMETT, also for pediatric patients. Right now, ISMETT is in the process of initiating a pancreas and pancreatic cell transplant program. The abdominal and thoracic transplant programs fall within the scope of the high-specialty hepatology, interventional radiology and endoscopy, abdominal surgery, nephrology, cardiology, and cardiac surgery aiming at preventing and treating heart, liver, and kidney failure.