Hepato-Bilio-Pancreatic Surgery

At IRCCS ISMETT, patients have access to state-of-the-art technology that allows to diagnose and treat a wide range of hepatic, biliary, and pancreatic diseases.

In Sicily, IRCCS ISMETT performs 30% of all surgical procedures for these diseases, with a considerably low 30-day postoperative mortality rate: in 2017-2019, for liver malignant tumor resection it was 0.63%, and for pancreas it was 0%.

How to book your first visit at IRCCS ISMETT:

Hepatobiliary Diseases

Pancreatic and Periampullary Diseases

Our results


Hepatobiliary Diseases

Non-malignant liver diseases

  • Hepatic adenoma
  • Hepatic hemangioma
  • Hepatic cystadenoma
  • Simple hepatic cyst
  • Polycystic liver
  • Echinococcosis
  • Focal nodular hyperplasia

Malignant liver diseases

  • Primitive liver tumors: hepatocarcinoma, intrahepatic cholangiocarcinoma, extra-hepatic cholangiocarcinoma
  • Gallbladder cancer
  • Hepatic metastases from colorectal neoplasms
  • Hepatic metastases from non-colorectal neoplasms

Surgical treatments

  • Conventional liver resection
  • Two-stage liver resection (ALPPS)
  • Minimally invasive liver resection
  • Extrahepatic biliary tract resection and biliodigestive derivation
  • Minimally invasive liver lesion microwave ablation

Pancreatic and Periampullary Diseases

  • Pancreatic adenocarcinoma
  • Distal cholangiocarcinoma
  • Duodenal adenocarcinoma
  • Duodenal GIST
  • Ampulla of Vater tumors
  • Pancreatic cystic neoplasms: intraductal papillary mucinous neoplasms (IPMN), mucinous cystic neoplasms, serous cystic neoplasms, pseudopapillary cystic neoplasms.
  • Pancreatic neuroendocrine neoplasms

Surgical treatments

  • Pancreatic resections with conventional or minimally invasive technique: duodeno-cephalo-pancreatectomy, distal pancreatectomy (with and without spleen preservation), total pancreatectomy, intermediate pancreatectomy, enucleation.

The IRCCS ISMETT Hepato-Bilio-Pancreatic Surgery Unit has 20+ years of experience and has performed more than 1,400 liver resections and more than 500 pancreatic resections with traditional and minimally invasive techniques, with a multidisciplinary team of surgeons, endoscopists, radiologists, interventional radiologists, pathologists, oncologists, radiation therapists, hepatologists, and pancreatologists.

Our results

Our results